Skin Protectant Lotion | DIFINSA53


The Soothing, Protective
Difference is DIFINSA53™ Lotion


DIFINSA53™ Skin Protectant Lotion was developed by doctors to soothe and protect your skin during radiation therapy. Use DIFINSA53™ lotion to prevent, protect and relieve chafed, chapped or cracked skin exposed to radiation.



Doesn’t Sting, Doesn’t Stick


DIFINSA53DIFINSA53™ lotion contains a patent-pending formulation of ingredients that will soothe, not sting, your skin during radiation therapy. These ingredients include natural botanicals plus an active skin protectant called dimethicone 1%, which is clinically-proven to be non-irritating to the skin.

Clothing won’t stick to your skin because DIFINSA53™ lotion is non-greasy and absorbs quickly. It also has a light, pleasant aroma.



Safe to Use


Hypoallergenic and dermatologist-approved, DIFINSA53™ lotion is safe to use as directed before you have a radiation treatment, after your radiation treatment, and then everyday between treatments.

When your treatments are over, you’ll be safe applying DIFINSA53™ lotion to uncovered skin before you go outdoors, to help prevent, and protect from, the drying effects of wind and cold weather.



Easily Economical


Pump ActionDIFINSA53™ lotion comes in a pump-action metered-dose dispenser. Each time you press the dispenser, you receive the same amount of lotion. This makes it easy to apply only as much lotion as you need, without wasting any of it.

Because a little DIFINSA53™ lotion goes a long way, and prevents more serious skin problems from developing, the DIFINSA53™ difference also means greater economy in your skin care during radiation therapy.



DIFINSA53™ Lotion Delivers the Difference

  • Prevents, protects, and relieves chafed, chapped or cracked skin
  • Prevents, and protects from, the drying effects of wind and cold weather
  • Relieves skin irritation
  • Soothes and hydrates the skin
  • Non-greasy, fast-absorbing
  • Light, pleasant aroma
  • Hypoallergenic
  • Dermatologist-approved
  • Developed by doctors


Formulated to Make a Difference



The DIFINSA53™ difference begins with our proprietary, patent-pending formulation for DIFINSA53™ Skin Protectant Lotion


The proprietary DIFINSA53™ formulation is the result of over a decade of research and development by a multidisciplinary team at the University of Colorado Anschutz Medical Campus and ProTechSure Scientific, Inc. Our oncologists and dermatologists worked alongside pharmacologists and pharmaceutical scientists with expertise in formulating natural small-molecule compounds for easy absorption into the skin.

Today, they continue working to discover applications for new small-molecules in our laboratories equipped with state-of-the-art micro technology.



Five Key Ingredients


DIFINSA53™ Skin Protectant Lotion contains five key ingredients that we have formulated specifically for skin exposed to radiation: the active skin protectant fluid, dimethicone 1%, plus the natural botanicals silibinin (silybum), aloe vera and niacinamide, and the naturally occurring substance, hyaluronic acid.

As summarized below, each of these five ingredients contributes to the overall benefit you receive when using DIFINSA53™ Skin Protectant Lotion on your skin.



Dimethicone 1%

DimethiconeDimethicone 1% is the active skin protectant ingredient in DIFINSA53™ lotion. It is a silicone fluid derived from silicon, an abundant earth element. When applied, it forms a surface barrier that not only protects the skin from chaffing, chapping and other irritation, but also keeps the skin from losing moisture and drying out. The widely spaced molecules of its chemical structure prevent moisture loss, while allowing the skin to breathe and not feel blocked or plugged up. Dimethicone 1% has been a well-established ingredient in cosmetic products since the 1950’s. It is clinically proven to be safe to use and non-irritating to the skin.

Silybin (Silibinin)

SilibininSilibinin, one of the most promising botanicals currently being studied for cellular health in the skin, is a natural extract from the milk thistle plant, which has been used safely and effectively for centuries to treat inflammation and other health conditions.

Long focused on silibinin research, our scientists have developed a proprietary formulation, based on extensive verification testing of its molecular characteristics, using high-performance liquid chromatography (HPLC) and mass spectrometry technologies.

As a result, DIFINSA53™ Skin Protectant Lotion is the first topical skin product available to contain silibinin. Moreover, the silibinin in DIFINSA53™ lotion is 95% pure, the highest purity available in a skin lotion.



Aloe VeraOne of the most ancient remedies known, aloe vera is the inner gel extracted from the leaves of the aloe barbadensis plant. Aloe vera remains a foundational natural ingredient in modern skin care formulations. Its strongest benefits may be its ability to hold moisture in the skin, keep pores clear and provide a refreshing sensation on the skin. In fact, aloe vera itself is 99.5% water!

Hyaluronic Acid

Hyaluronic AcidHyaluronic acid is actually not an acid, but a carbohydrate compound that occurs naturally in the human body, mostly in the eyes, skin and joint cartilage. In the skin, it forms a kind of natural gel in the spaces between the cells. It cushions the skin cells, helping to protect them, and also stores water for the cells, helping to keep the skin hydrated.

There are many medical uses for hyaluronic acid. In skin care products, it helps add firmness, suppleness and moisture to damaged or aging skin. It is also used as a filler in cosmetic surgery procedures.


NiacinamideNiacinamide is a form of niacin, better known as vitamin B3, which is found naturally in vegetables, milk, eggs, and many other foods. Its main medicinal use is to treat niacin deficiency due to illness or poor diet, and high cholesterol. Used topically on the skin, niacin has been shown to bolster the epidermis, helping the skin to retain its water content. In addition, niacinamide is thought to play a role in improving the skin’s elasticity, reducing skin discoloration, and reviving skin tone and texture.



Start Feeling the Difference Yourself!


Feel the Difference You don’t need a prescription for DIFINSA53™ lotion. Either obtain it from your doctor or order it here on our website.

Be sure to talk with your doctor or nurse before using DIFINSA53™ lotion. Although DIFINSA53™ lotion is hypoallergenic and dermatologist-approved, it’s always a good idea to let them know about any allergies you have. Also tell them about any prescription skin care medications you are using.

If you have questions about DIFINSA53™ lotion that are not answered on this website, please talk with your doctor or nurse, or email us and we’ll respond to you quickly.